Microdosing Guides
Microdosing Safety & Education Resources
Microdosing Research Safety Notice You can download a PDF version of this guide by clicking here. Please read the following information carefully. About Microdosing As experienced microdosers, [...]
Microdosing with Precision (LSD)
Microdosing with precision (LSD) You can download a PDF version of this guide by clicking here. LSD is dispensed in various commonly available forms: as a concentrated [...]
Videos
Recommended videos and lectures
Dr. Robin Carhart-Harris presents us with an overview of his research involving brain imaging studies and other pioneering studies with psychedelics at TEDx 2016.
James Fadiman presents findings of his large scale study on microdosing psychedelics. Presented at Psychedelic Science 2017.
James Fadiman and Ayelet Waldman (author of A Really Good Day:How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life ) give a talk on microdosing which includes a thought provoking QnA with the audience.
Blog
What is Microdosing?
What is Microdosing? “Microdosing” is the practice of ingesting small, sub-perceptual amounts of psychedelics such as LSD, psilocybin, and mescaline. Microdosing has become an increasingly prevalent [...]
A brief history of LSD
A brief history of LSD A brief history of LSD LSD was first synthesized by Albert Hofmann in 1938 as part of a systematic study [...]
Journal Articles
Expand your knowledge with these selected research articles
Neurobiology
Effective connectivity changes in LSD-induced altered states of consciousness in humans (2019). Preller, K. H., Raazi, A., Zeidman, P., Stampfli, P., Kriston, K. J. & Vollenweider, F. X. PNAS 116(7), 2743-2748.
Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor (2018). Preller, K. H., Burt, J. B., Ji, J. L., Schleifer, C. H., Adkinson, B.D., Stämpfli, P., Seifritz, E., Repovs, G., Krystal, J. H., Murray, J. D., Vollenweider, F. X. & Anticevic, A. eLife Oct 25, 7. doi: 10.7554/eLife.35082.
Microdosing
Psychedelic microdosing benefits and challenges: and empirical codebook (2019). Anderson, T., Petranker, R., Christopher, A., Rosenbaum, D., Weissman, C., Dihn-Williams, L., …Hapke, E. Harm Reduction Journal, 16(43). doi: doi.org/10.1186/s12954-019-0308-4
Acute subjective and behavioral effects of microdoses of LSD in healthy human volunteers (2019). Bershad, A., Schepers, S., Bremmer, M., Lee, R., & de Witt, H.. Biological Psychiatry, doi: doi.org/10.1016/j.biopsych.2019.05.019.
Cosmetic consciousness: Cross-sectional exploration of the microdosing community and empirical examination of anecdotal benefits. Camps, R. (2017). (Unpublished Research Project from Goldsmiths, University of London).
Might Microdosing Psychedelics Be Safe and Beneficial? An Initial Exploration (2019). Fadiman, J. & Korb, S. Journal of Psychoactive Drugs, March 29:1-5. doi: 10.1080/02791072.2019.1593561.
Safety, tolerability, pharmacokinetics, and pharmacodynamics of low dose lysergic acid diethylamide (LSD) in healthy older volunteers (2019). Family, N., Maillet, E., Williams, L., Krediet, E., Carhart-Harris, R., Williams, T… Raz, S. Psychopharmacology. 1-13, doi.org/10.1007/s00213-019-05417-7
Motives and Side-Effects of Microdosing With Psychedelics Among Users (2019). Hutten, N., Mason, N., Dolder, P., & Kuypers, P. International Journal of Neuropsychopharmacology, 22(7), 426–434. doi:10.1093/ijnp/pyz029
Self-Rated Effectiveness of Microdosing With Psychedelics for Mental and Physical Health Problems Among Microdosers (2019). Hutten, N., Mason, N., Dolder, P., & Kuypers, P. Frontiers in Psychiatry, 10(672) doi: 10.3389/fpsyt.2019.00672
Powerful substances in tiny amounts: An interview study of psychedelic microdosing (2018). Johnstad, P. Nordic Studies on Alcohol and Drugs, 35(1), 39-51. https://doi.org/10.1177/1455072517753339
Microdosing psychedelics: Motivations, subjective effects and harm reduction (2020). Lea, T., Amada, N., Jungaberle, H., Schecke, H., Klein, M. International Journal of Drug Policy. 75, 102600. doi: doi.org/10.1016/j.drugpo.2019.11.008
Perceived outcomes of psychedelic microdosing as self-managed therapies for mental and substance use disorders (2020). Lea, T., Amada, N., Jungaberle, H., Schecke, H., Scherbaum, N., Klein, M. Psychopharmacology.237(5), 1521-1532 doi: doi.org/10.1007/s00213-020-05477-0
The science of microdosing (2019). Passie, T. London, UK: Psychedelic Press.
A systematic study of microdosing psychedelics (2019). Polito V., Stevenson R. PLoS ONE 14(2): e0211023. https://doi.org/10.1371/journal.pone.0211023
Microdosing psychedelics: demographics, practices, and psychiatric comorbidities (2020). Rosenbaum, D., Weissman, C., Anderson, T., Petranker, R., Dihn-Williams, L., Hui, K., Hapke, E. (2020). Journal of Psychopharmacology. https://journals.sagepub.com/doi/10.1177/0269881120908004
The effects of microdose LSD on time perception: a randomised, double-blind, placebo-controlled trial (2018). Yanakieva S., Polychroni N., Family N., Williams L. T. J., Luke, D. P. & Terhune D. B. Psychopharmacology Nov 26. doi: 10.1007/s00213-018-5119-x.
Clinical and therapeutic applications
Modern Clinical Research on LSD (2017). Liechti, M. E. Neuropsychopharmacology, 42(11): 2114–2127.
Psychedelic-Assisted Group Therapy: A Systematic Review (2019). Trope, A., Anderson, B. T., Hooker, A. R., Glick, G., Stauffer, C. & Woolley, J. D. Journal of Psychoactive Drugs, Apr 5: 1-15. doi: 10.1080/02791072.2019.1593559.
LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice (2018). Alper, K., Dong, B., Shah, R., Sershen, H. & Vinod, K. Y. Frontiers in Pharmacology, 9, 994. doi: 10.3389/fphar.2018.00994.